Kyle Kasparian

Entered Combined-Degree Program: Fall 2020 as entering DMD student.


Kyle Kasparian

Kyle Kasparian grew up in Long Grove, Illinois, a small suburb of Chicago. He attended DePaul University, where he graduated Suma Cum Laude with a major in Biological Sciences and a minor in Business Administration. At DePaul, he worked in a molecular neuroscience laboratory studying the role of the polymorphic gene, APOE, on the pathogenesis of Alzheimer’s Disease and other neurodegenerative diseases. Kyle specifically focused on studying inflammatory responses and inflammatory forms of cell death across APOE genotypes utilizing both in vivo and in vitro methods. This experience fostered his interest in the association between periodontal disease and various neurodegenerative diseases, most notably being Alzheimer’s Disease, and the molecular mechanisms underlying this association.

Kyle was also a Supplemental Instruction Leader of Organic Chemistry at DePaul University, allowing him to play an active role in teaching students. He greatly enjoys teaching and hopes to become a successful clinician-scientist dedicated to teaching, research, and clinical care.

In his free time, Kyle enjoys biking outdoors and playing board games with friends. He also serves as the D1 Class Representative of the National Student Research Group (NSRG) of the American Association of Dental Research.


Graykowski D, Kasparian K, Caniglia J, Gritsaeva Y, Cudaback E. Neuroinflammation drives APOE genotype-dependent differential expression of neprilysin. J Neuroimmunol. 2020; 346:577315. doi: 10.1016/j.jneuroim.2020.577315. [Epub ahead of print] PubMed PMID: 32682137.
(Accepted, in production) Kasparian K, Graykowski D, Cudaback E. Commentary: APOE E4 Predicts Severe COVID-19 in the UK Biobank Community Cohort. Front. Immunol. 2020; 11:1939. doi: 10.3389/fimmu.2020.01939.