Yenisel Cruz-Almeida, MSPH, Ph.D.
Associate Professor & Associate Director, Pain Research & Intervention Center Of Excellence
About Yenisel Cruz-Almeida
Dr. Cruz-Almeida was born in La Habana, Cuba. She completed a B.Sc. degree in Microbiology & Cell Science from the University of Florida, followed by a Master’s degree in Epidemiology & Public Health with a concentration in Biostatistics, and a Ph.D. in Neuroscience at the Miami Project to Cure Paralysis from the University of Miami MILLER School of Medicine. Yenisel is currently a tenured Associate Professor in the Department of Community Dentistry and Behavioral Sciences, as well as affiliate faculty in the Departments of Epidemiology and Neuroscience. Dr Cruz-Almeida serves as the Associate Director of the UF Pain Research & Intervention Center of Excellence. She is the Course Director of GMS 6711 (Neurobiology of Pain), DEN 6251 (Science and Clinical Management of Dental Pain), and GMS 6895 (Clinical Translational Sciences Journal Club).
Additional Positions:
Core Leader
2018 – Current
·
Older American Independence Center
Teaching Profile
Courses Taught
2016,2018-2022
GMS6895 CTS Journal Club
2013-2018,2020-2024
DEN6251 Clin Manage Dent Pain
2017-2020
GMS6771 Clinical Neuroscience of Aging
2014,2020
DEN5221 Oral Hlth Manage
2019-2020
GMS6905 Independent Studies in Medical Sciences
2019-2020
GMS6090 Research in Medical Sciences
2015,2018-2019
GMS6711 Neurobiology of Pain
2017-2018
HSC4970 Public Health and Health Professions Senior Honors Thesis
2018
EGN4912 Engineering Directed Independent Research
2013-2015
GMS6417 Integrative Aging Physiology
2015
GMS6845 Clinical & Translational Research Practicum
2014
GMS7794 Neuroscience Seminar
2013
DEN6001 Intr Evdnce Dent Prac
2022-2023
HSC4913 Supervised Research Experience
2022-2024
GMS7979 Advanced Research
2024
GMS7980 Research for Doctoral Dissertation
Research Profile
Chronic pain represents the most prevalent and expensive public health condition in the United States, affecting 100 million people in the country with annual costs to society estimated at $635 billion. This exceeds the combined costs of cancer, AIDS, and heart disease. As a clinical translational neuroscientist, my research interests are related to understanding pain perception and modulation in humans across the lifespan. Using multiple interdisciplinary and translational approaches including psychophysics, neuroimaging, and epigenetics, my research examines nervous system factors contributing to the observed inter-individual differences in pain phenotypes and its functional consequences including cognitive and mobility outcomes.
Open Researcher and Contributor ID (ORCID)
0000-0002-0065-0236
Publications
2024
A multi-modal evaluation of experimental pain and psychological function in women with carpometacarpal osteoarthritis
Osteoarthritis and Cartilage Open.
6(4)
[DOI] 10.1016/j.ocarto.2024.100515.
[PMID] 39286574.
2024
Accelerated Brain Aging Mediates the Association Between Psychological Profiles and Clinical Pain in Knee Osteoarthritis
The Journal of Pain.
25(5)
[DOI] 10.1016/j.jpain.2023.11.006.
[PMID] 37952863.
2024
Addressing Pain Using a Mediterranean Ketogenic Nutrition Program in Older Adults with Mild Cognitive Impairment
Journal of Pain Research.
Volume 17:1867-1880
[DOI] 10.2147/jpr.s451236.
2024
Association of Muscle Quality and Pain in Adults With Symptomatic Knee Osteoarthritis, Independent of Muscle Strength: Findings From a Cross-Sectional Study.
Arthritis & rheumatology (Hoboken, N.J.).
76(7):1062-1070
[DOI] 10.1002/art.42834.
[PMID] 38403452.
2024
Author Correction: Weight-cycling over 6 years is associated with pain, physical function and depression in the Osteoarthritis Initiative cohort.
Scientific reports.
14(1)
[DOI] 10.1038/s41598-024-52366-z.
[PMID] 38242955.
2024
Beyond numbers: integrating qualitative analysis into quantitative sensory testing for neuropathic pain.
Frontiers in pain research (Lausanne, Switzerland).
5
[DOI] 10.3389/fpain.2024.1351602.
[PMID] 38486872.
2024
Body composition and body mass index are independently associated with widespread pain and experimental pain sensitivity in older adults: a pilot investigation.
Frontiers in pain research (Lausanne, Switzerland).
5
[DOI] 10.3389/fpain.2024.1386573.
[PMID] 39015155.
2024
Chronic Pain Among Middle-Aged and Older Adults in the United States: The Role of Everyday Discrimination and Racial/Ethnic Identity
The Journal of Pain.
25(5)
[DOI] 10.1016/j.jpain.2023.11.022.
[PMID] 38065467.
2024
ENIGMA-Chronic Pain: a worldwide initiative to identify brain correlates of chronic pain
Pain.
[DOI] 10.1097/j.pain.0000000000003317.
2024
Epigenetic Aging: A Socio-Biological Link to Chronic Pain?
The Journal of Pain.
25(2):572-573
[DOI] 10.1016/j.jpain.2023.11.007.
2024
Food insecurity and epigenetic aging in middle-aged and older adults.
Social science & medicine (1982).
350
[DOI] 10.1016/j.socscimed.2024.116949.
[PMID] 38723585.
2024
Food insecurity is associated with chronic pain and high-impact chronic pain in the USA
Public Health Nutrition.
27(1)
[DOI] 10.1017/s1368980023002732.
2024
High-Impact Pain Is Associated With Epigenetic Aging Among Middle-Aged and Older Adults: Findings From the Health and Retirement Study
The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences.
79(8)
[DOI] 10.1093/gerona/glae149.
[PMID] 38855906.
2024
Lower individual alpha frequency in individuals with chronic low back pain and fear of movement.
Pain.
165(5):1033-1043
[DOI] 10.1097/j.pain.0000000000003098.
[PMID] 38112575.
2024
Measurement of Pain Frequency Associated With Knee Osteoarthritis: Future Directions
The Journal of Pain.
25(10)
[DOI] 10.1016/j.jpain.2024.104545.
2024
Socioeconomic Status, Knee Pain, and Epigenetic Aging in Community-Dwelling Middle-to-Older Age Adults
The Journal of Pain.
25(2):293-301
[DOI] 10.1016/j.jpain.2023.06.002.
[PMID] 37315728.
2023
A Secondary Analysis: Comparison of Experimental Pain and Psychological Impact in Individuals with Carpometacarpal and Knee Osteoarthritis
Journal of Pain Research.
Volume 16:4139-4149
[DOI] 10.2147/jpr.s421689.
2023
Brain predicted age difference mediates pain impact on physical performance in community dwelling middle to older aged adults.
Geriatric nursing (New York, N.Y.).
50:181-187
[DOI] 10.1016/j.gerinurse.2023.01.019.
[PMID] 36787663.
2023
Brain-predicted age difference estimated using DeepBrainNet is significantly associated with pain and function—a multi-institutional and multiscanner study
Pain.
164(12):2822-2838
[DOI] 10.1097/j.pain.0000000000002984.
[PMID] 37490099.
2023
Brain-predicted age difference mediates the association between PROMIS sleep impairment, and self-reported pain measure in persons with knee pain
Aging Brain.
4
[DOI] 10.1016/j.nbas.2023.100088.
[PMID] 37519450.
2023
Characteristics and Outcomes of Patients Receiving Physical Therapy for Low Back Pain with a Nociplastic Pain Presentation: A Secondary Analysis
Pain Research and Management.
2023:1-10
[DOI] 10.1155/2023/5326261.
[PMID] 36935875.
2023
Electrical Brain Activity during Human Walking with Parametric Variations in Terrain Unevenness and Walking Speed.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2023.07.31.551289.
[PMID] 37577540.
2023
Epigenetic age acceleration mediates the relationship between neighborhood deprivation and pain severity in adults with or at risk for knee osteoarthritis pain.
Social science & medicine (1982).
331
[DOI] 10.1016/j.socscimed.2023.116088.
[PMID] 37473540.
2023
Expectations affect pain sensitivity changes during massage.
The Journal of manual & manipulative therapy.
31(2):84-92
[DOI] 10.1080/10669817.2022.2118449.
[PMID] 36069038.
2023
Feasibility of brain age predictions from clinical T1-weighted MRIs
Brain Research Bulletin.
205
[DOI] 10.1016/j.brainresbull.2023.110811.
2023
More Problems, More Pain: The Role of Chronic Life Stressors and Racial/Ethnic Identity on Chronic Pain Among Middle-Aged and Older Adults in the United States.
Chronic stress (Thousand Oaks, Calif.).
7
[DOI] 10.1177/24705470231208281.
[PMID] 37881639.
2023
Pain interference mediates the association between epigenetic aging and grip strength in middle to older aged males and females with chronic pain.
Frontiers in aging neuroscience.
15
[DOI] 10.3389/fnagi.2023.1122364.
[PMID] 37032822.
2023
Pain phenotyping and investigation of outcomes in physical therapy: An exploratory study in patients with low back pain.
PloS one.
18(2)
[DOI] 10.1371/journal.pone.0281517.
[PMID] 36787322.
2023
Pain severity, distribution, and duration are associated with spatiotemporal gait performance in community-dwelling older adults with chronic musculoskeletal pain.
Gait & posture.
103:178-183
[DOI] 10.1016/j.gaitpost.2023.05.011.
[PMID] 37236053.
2023
Protocol for a pilot and feasibility randomized-controlled trial of four weeks of oral γ-aminobutyric acid (GABA) intake and its effect on pain and sleep in middle-to-older aged adults
Contemporary Clinical Trials Communications.
32
[DOI] 10.1016/j.conctc.2023.101066.
[PMID] 36712186.
2023
Self-reported pain and fatigue are associated with physical and cognitive function in middle to older-aged adults.
Geriatric nursing (New York, N.Y.).
50:7-14
[DOI] 10.1016/j.gerinurse.2022.12.015.
[PMID] 36640518.
2023
Toward MR protocol-agnostic, bias-corrected brain age predicted from clinical-grade MRIs.
Research square.
[DOI] 10.21203/rs.3.rs-3229072/v1.
[PMID] 37609150.
2023
Toward MR protocol-agnostic, unbiased brain age predicted from clinical-grade MRIs.
Scientific reports.
13(1)
[DOI] 10.1038/s41598-023-47021-y.
[PMID] 37950024.
2023
Uneven terrain versus dual-task walking: differential challenges imposed on walking behavior in older adults are predicted by cognitive and sensorimotor function.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2023.03.14.531779.
[PMID] 36993462.
2023
Vitamin D Metabolism Genes Are Differentially Methylated in Individuals with Chronic Knee Pain
Lifestyle Genomics.
98-105
[DOI] 10.1159/000529823.
[PMID] 36854277.
2023
Weight-cycling over 6 years is associated with pain, physical function and depression in the Osteoarthritis Initiative cohort.
Scientific reports.
13(1)
[DOI] 10.1038/s41598-023-44052-3.
[PMID] 37813940.
2022
Accelerated Epigenetic Aging Mediates the Association between Vitamin D Levels and Knee Pain in Community-Dwelling Individuals.
The journal of nutrition, health & aging.
26(4):318-323
[DOI] 10.1007/s12603-022-1758-z.
[PMID] 35450986.
2022
Advancing our understanding of neuropathic pain in diabetes mellitus using conditioned pain modulation: further considerations for age and testing site.
Pain.
163(5):805-806
[DOI] 10.1097/j.pain.0000000000002441.
[PMID] 34382605.
2022
Analysis of AVPR1A, thermal and pressure pain thresholds, and stress in sickle cell disease.
Frontiers in pain research (Lausanne, Switzerland).
3
[DOI] 10.3389/fpain.2022.1060245.
[PMID] 36688082.
2022
Autonomic Nervous System Dysregulation and Osteoarthritis Pain: Mechanisms, Measurement, and Future Outlook.
Current rheumatology reports.
24(6):175-183
[DOI] 10.1007/s11926-022-01071-9.
[PMID] 35420372.
2022
Chronic Musculoskeletal Pain Moderates the Association between Sleep Quality and Dorsostriatal-Sensorimotor Resting State Functional Connectivity in Community-Dwelling Older Adults
Pain Research and Management.
2022:1-12
[DOI] 10.1155/2022/4347759.
[PMID] 35432664.
2022
Clinical vitamin D levels are associated with insular volume and inferior temporal gyrus white matter surface area in community-dwelling individuals with knee pain.
Frontiers in neuroscience.
16
[DOI] 10.3389/fnins.2022.882322.
[PMID] 36117614.
2022
Cross-Sectional Brain-Predicted Age Differences in Community-Dwelling Middle-Aged and Older Adults with High Impact Knee Pain
Journal of Pain Research.
Volume 15:3575-3587
[DOI] 10.2147/jpr.s384229.
2022
Decreased cognitive function is associated with impaired spatiotemporal gait performance in community dwelling older adults with chronic musculoskeletal pain.
Brain and cognition.
159
[DOI] 10.1016/j.bandc.2022.105862.
[PMID] 35358922.
2022
Differential DNA methylation in Black and White individuals with chronic low back pain enrich different genomic pathways.
Neurobiology of pain (Cambridge, Mass.).
11
[DOI] 10.1016/j.ynpai.2022.100086.
[PMID] 35243180.
2022
Enrichment of genomic pathways based on differential DNA methylation profiles associated with knee osteoarthritis pain.
Neurobiology of pain (Cambridge, Mass.).
12
[DOI] 10.1016/j.ynpai.2022.100107.
[PMID] 36531611.
2022
Epigenetic age predictors in community-dwelling adults with high impact knee pain
Molecular Pain.
18
[DOI] 10.1177/17448069221118004.
[PMID] 35968561.
2022
Epigenetic Aging Mediates the Association between Pain Impact and Brain Aging in Middle to Older Age Individuals with Knee Pain.
Epigenetics.
17(13):2178-2187
[DOI] 10.1080/15592294.2022.2111752.
[PMID] 35950599.
2022
Epigenetic aging, knee pain and physical performance in community-dwelling middle-to-older age adults.
Experimental gerontology.
166
[DOI] 10.1016/j.exger.2022.111861.
[PMID] 35640781.
2022
Experimental Pain Phenotype Profiles in Community-dwelling Older Adults
Clinical Journal of Pain.
38(7):451-458
[DOI] 10.1097/AJP.0000000000001048.
2022
Gait subgroups among older adults with chronic pain differ in cerebellum and basal ganglia gray matter volumes.
Experimental gerontology.
163
[DOI] 10.1016/j.exger.2022.111773.
[PMID] 35341939.
2022
HUMAN STUDY COMT and DRD3 haplotype-associated pain intensity and acute care utilization in adult sickle cell disease.
Experimental biology and medicine (Maywood, N.J.).
247(17):1601-1608
[DOI] 10.1177/15353702221080716.
[PMID] 35285297.
2022
Persistent Non-pharmacological Pain Management and Brain-Predicted Age Differences in Middle-Aged and Older Adults With Chronic Knee Pain.
Frontiers in pain research (Lausanne, Switzerland).
3
[DOI] 10.3389/fpain.2022.868546.
[PMID] 35903307.
2021
A psychophysical study comparing massage to conditioned pain modulation: A single blind randomized controlled trial in healthy participants.
Journal of bodywork and movement therapies.
27:426-435
[DOI] 10.1016/j.jbmt.2021.02.014.
[PMID] 34391267.
2021
Additional considerations for studying brain metabolite levels across pain conditions using proton magnetic resonance spectroscopy
NeuroImage.
224
[DOI] 10.1016/j.neuroimage.2020.117392.
2021
Age Differences in Multimodal Quantitative Sensory Testing and Associations With Brain Volume
Innovation in Aging.
5(3)
[DOI] 10.1093/geroni/igab033.
[PMID] 34616958.
2021
Brain gamma-aminobutyric acid, but not glutamine and glutamate levels are lower in older adults with chronic musculoskeletal pain: considerations by sex and brain location
PAIN Reports.
6(3)
[DOI] 10.1097/pr9.0000000000000952.
2021
Chronic oxytocin administration in older men modulates functional connectivity during animacy perception.
Aging brain.
1
[DOI] 10.1016/j.nbas.2021.100023.
[PMID] 36911518.
2021
Chronic Pain is Associated With Reduced Sympathetic Nervous System Reactivity During Simple and Complex Walking Tasks: Potential Cerebral Mechanisms.
Chronic stress (Thousand Oaks, Calif.).
5
[DOI] 10.1177/24705470211030273.
[PMID] 34286166.
2021
Pain and the Montreal Cognitive Assessment (MoCA) in Aging
Pain Medicine.
[DOI] 10.1093/pm/pnab003.
[PMID] 33718961.
2021
Pain differences in neurite orientation dispersion and density imaging measures among community-dwelling older adults.
Experimental gerontology.
154
[DOI] 10.1016/j.exger.2021.111520.
[PMID] 34418483.
2021
Psychological profiles in adults with knee OA-related pain: a replication study.
Therapeutic advances in musculoskeletal disease.
13
[DOI] 10.1177/1759720X211059614.
[PMID] 34900003.
2021
Resting-state functional connectivity patterns are associated with worst pain duration in community-dwelling older adults.
Pain reports.
6(4)
[DOI] 10.1097/PR9.0000000000000978.
[PMID] 34901680.
2021
The Imperative for Racial Equality in Pain Science: A Way Forward.
The journal of pain.
22(12):1578-1585
[DOI] 10.1016/j.jpain.2021.06.008.
[PMID] 34214701.
2021
Treatment of localized aggressive periodontitis alters local host immunoinflammatory profiles: A long‐term evaluation
Journal of Clinical Periodontology.
48(2):237-248
[DOI] 10.1111/jcpe.13404.
[PMID] 33205510.
2020
Cortical Thickness Mediates the Association Between Self-Reported Pain and Sleep Quality in Community-Dwelling Older Adults
Journal of Pain Research.
Volume 13:2389-2400
[DOI] 10.2147/jpr.s260611.
2020
A Novel Approach to Characterizing Readmission Patterns Following Hospitalization for Ambulatory Care-Sensitive Conditions.
Journal of general internal medicine.
35(4):1060-1068
[DOI] 10.1007/s11606-020-05643-2.
[PMID] 31993948.
2020
Age does not affect sex effect of conditioned pain modulation of pressure and thermal pain across 2 conditioning stimuli.
Pain reports.
5(1)
[DOI] 10.1097/PR9.0000000000000796.
[PMID] 32072094.
2020
Corrigendum: Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults (Mind in Motion Study): Hypothesis, Theory, and Methods.
Frontiers in aging neuroscience.
12
[DOI] 10.3389/fnagi.2020.00063.
[PMID] 32194394.
2020
Enrichment of genomic pathways based on differential DNA methylation profiles associated with chronic musculoskeletal pain in older adults: An exploratory study
Molecular Pain.
16
[DOI] 10.1177/1744806920966902.
[PMID] 33073674.
2020
Innovations in Geroscience to enhance mobility in older adults.
Experimental gerontology.
142
[DOI] 10.1016/j.exger.2020.111123.
[PMID] 33191210.
2020
Pain Severity and Interference in Different Parkinson’s Disease Cognitive Phenotypes
Journal of Pain Research.
Volume 13:3493-3497
[DOI] 10.2147/jpr.s270669.
2020
Pain, aging, and the brain: new pieces to a complex puzzle.
Pain.
161(3):461-463
[DOI] 10.1097/j.pain.0000000000001757.
[PMID] 31764392.
2019
Age and pain differences in non-verbal fluency performance: Associations with cortical thickness and subcortical volumes.
Experimental gerontology.
126
[DOI] 10.1016/j.exger.2019.110708.
[PMID] 31445107.
2019
Chronic pain is associated with a brain aging biomarker in community-dwelling older adults.
Pain.
160(5):1119-1130
[DOI] 10.1097/j.pain.0000000000001491.
[PMID] 31009418.
2019
Effects of manipulating the interstimulus interval on heat-evoked temporal summation of second pain across the age span.
Pain.
160(1):95-101
[DOI] 10.1097/j.pain.0000000000001382.
[PMID] 30169423.
2019
Epigenetic aging is associated with clinical and experimental pain in community-dwelling older adults
Molecular Pain.
15
[DOI] 10.1177/1744806919871819.
[PMID] 31394966.
2019
Movement-evoked pain, physical function, and perceived stress: An observational study of ethnic/racial differences in aging non-Hispanic Blacks and non-Hispanic Whites with knee osteoarthritis.
Experimental gerontology.
124
[DOI] 10.1016/j.exger.2019.05.011.
[PMID] 31154005.
2019
Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults (Mind in Motion Study): Hypothesis, Theory, and Methods.
Frontiers in aging neuroscience.
11
[DOI] 10.3389/fnagi.2019.00358.
[PMID] 31969814.
2019
Musculoskeletal Pain and Brain Morphology: Oxytocin’s Potential as a Treatment for Chronic Pain in Aging.
Frontiers in aging neuroscience.
11
[DOI] 10.3389/fnagi.2019.00338.
[PMID] 31920621.
2019
Resilience factors may buffer cellular aging in individuals with and without chronic knee pain.
Molecular pain.
15
[DOI] 10.1177/1744806919842962.
[PMID] 30900507.
2019
The impact of multisite pain on functional outcomes in older adults: biopsychosocial considerations.
Journal of pain research.
12:1115-1125
[DOI] 10.2147/JPR.S192755.
[PMID] 30992680.
2018
Knee osteoarthritis: pathophysiology and current treatment modalities.
Journal of pain research.
11:2189-2196
[DOI] 10.2147/JPR.S154002.
[PMID] 30323653.
2018
Omega-6: Omega-3 PUFA Ratio, Pain, Functioning, and Distress in Adults With Knee Pain.
The Clinical journal of pain.
34(2):182-189
[DOI] 10.1097/AJP.0000000000000517.
[PMID] 28542024.
2018
Systemic Inflammation Mediates Age-Related Cognitive Deficits.
Frontiers in aging neuroscience.
10
[DOI] 10.3389/fnagi.2018.00236.
[PMID] 30127734.
2017
Accelerated aging in adults with knee osteoarthritis pain: consideration for frequency, intensity, time, and total pain sites.
Pain reports.
2(3)
[DOI] 10.1097/PR9.0000000000000591.
[PMID] 29392207.
2017
Age Differences in Salivary Markers of Inflammation in Response to Experimental Pain: Does Venipuncture Matter?
Journal of pain research.
10:2365-2372
[DOI] 10.2147/JPR.S138460.
[PMID] 29042812.
2017
Age Differences in the Time Course and Magnitude of Changes in Circulating Neuropeptides After Pain Evocation in Humans.
The journal of pain.
18(9):1078-1086
[DOI] 10.1016/j.jpain.2017.04.006.
[PMID] 28461253.
2017
Associations of Musculoskeletal Pain With Mobility in Older Adults: Potential Cerebral Mechanisms.
The journals of gerontology. Series A, Biological sciences and medical sciences.
72(9):1270-1276
[DOI] 10.1093/gerona/glx084.
[PMID] 28505228.
2017
Cytokine response patterns to complex biofilms by mononuclear cells discriminate patient disease status and biofilm dysbiosis.
Journal of oral microbiology.
9(1)
[DOI] 10.1080/20002297.2017.1330645.
[PMID] 28748035.
2017
Increased spatial dimensions of repetitive heat and cold stimuli in older women.
Pain.
158(5):973-979
[DOI] 10.1097/j.pain.0000000000000709.
[PMID] 27598411.
2017
Local and Plasma Biomarker Profiles in Localized Aggressive Periodontitis.
JDR clinical and translational research.
2(3):258-268
[DOI] 10.1177/2380084417701898.
[PMID] 28879248.
2017
Loss of Temporal Inhibition of Nociceptive Information Is Associated With Aging and Bodily Pain.
The journal of pain.
18(12):1496-1504
[DOI] 10.1016/j.jpain.2017.08.003.
[PMID] 28847735.
2017
Methodological Considerations for the Temporal Summation of Second Pain.
The journal of pain.
18(12):1488-1495
[DOI] 10.1016/j.jpain.2017.07.009.
[PMID] 28801070.
2017
Physical performance and movement-evoked pain profiles in community-dwelling individuals at risk for knee osteoarthritis.
Experimental gerontology.
98:186-191
[DOI] 10.1016/j.exger.2017.08.026.
[PMID] 28842222.
2017
Single Nucleotide Polymorphism in the COL11A2 Gene Associated with Heat Pain Sensitivity in Knee Osteoarthritis.
Molecular pain.
13
[DOI] 10.1177/1744806917724259.
[PMID] 28741447.
2017
Testing Assumptions in Human Pain Models: Psychophysical Differences Between First and Second Pain.
The journal of pain.
18(3):266-273
[DOI] 10.1016/j.jpain.2016.10.019.
[PMID] 27888117.
2016
Enhanced Pain Sensitivity Among Individuals With Symptomatic Knee Osteoarthritis: Potential Sex Differences in Central Sensitization.
Arthritis care & research.
68(4):472-80
[DOI] 10.1002/acr.22712.
[PMID] 26434740.
2016
Experimental pain phenotyping in community-dwelling individuals with knee osteoarthritis.
Pain.
157(9):2104-2114
[DOI] 10.1097/j.pain.0000000000000625.
[PMID] 27340911.
2016
Inflammatory Response Influences Treatment of Localized Aggressive Periodontitis.
Journal of dental research.
95(6):635-41
[DOI] 10.1177/0022034516631973.
[PMID] 26917438.
2016
Moving beyond the eigenvalue greater than one retention criteria in pain phenotyping research.
Pain.
157(6):1363-1364
[DOI] 10.1097/j.pain.0000000000000520.
[PMID] 27183445.
2016
Novel method for assessing age-related differences in the temporal summation of pain.
Journal of pain research.
9:195-205
[DOI] 10.2147/JPR.S102379.
[PMID] 27114716.
2015
A Cross-sectional Examination of Vitamin D, Obesity, and Measures of Pain and Function in Middle-aged and Older Adults With Knee Osteoarthritis.
The Clinical journal of pain.
31(12):1060-7
[DOI] 10.1097/AJP.0000000000000210.
[PMID] 25569220.
2015
Age Differences in Cytokine Expression Under Conditions of Health Using Experimental Pain Models
Experimental Gerontology.
72:150-156
[DOI] 10.1016/j.exger.2015.09.017.
[PMID] 26456458.
2015
Age-related differences in conditioned pain modulation of sensitizing and desensitizing trends during response dependent stimulation.
Behavioural brain research.
289:61-8
[DOI] 10.1016/j.bbr.2015.04.014.
[PMID] 25907744.
2015
Aging, the Central Nervous System, and Mobility in Older Adults: Neural Mechanisms of Mobility Impairment.
The journals of gerontology. Series A, Biological sciences and medical sciences.
70(12):1526-32
[DOI] 10.1093/gerona/glv130.
[PMID] 26386013.
2015
Disrupted sleep is associated with altered pain processing by sex and ethnicity in knee osteoarthritis.
The journal of pain.
16(5):478-90
[DOI] 10.1016/j.jpain.2015.02.004.
[PMID] 25725172.
2015
Reliability of pain intensity clamping using response-dependent thermal stimulation in healthy volunteers.
BMC neuroscience.
16
[DOI] 10.1186/s12868-015-0164-4.
[PMID] 25909597.
2015
Somatosensory phenotype is associated with thalamic metabolites and pain intensity after spinal cord injury.
Pain.
156(1):166-174
[DOI] 10.1016/j.pain.0000000000000019.
[PMID] 25599312.
2015
Successful aging: Advancing the science of physical independence in older adults.
Ageing research reviews.
24(Pt B):304-27
[DOI] 10.1016/j.arr.2015.09.005.
[PMID] 26462882.
2014
Age and race effects on pain sensitivity and modulation among middle-aged and older adults.
The journal of pain.
15(3):272-82
[DOI] 10.1016/j.jpain.2013.10.015.
[PMID] 24239561.
2014
Can quantitative sensory testing move us closer to mechanism-based pain management?
Pain medicine (Malden, Mass.).
15(1):61-72
[DOI] 10.1111/pme.12230.
[PMID] 24010588.
2014
Pain hypervigilance is associated with greater clinical pain severity and enhanced experimental pain sensitivity among adults with symptomatic knee osteoarthritis.
Annals of behavioral medicine : a publication of the Society of Behavioral Medicine.
48(1):50-60
[DOI] 10.1007/s12160-013-9563-x.
[PMID] 24352850.
2014
Psychological Resilience as a Predictor of Pain and Stress in Symptomatic Knee Osteoarthritis
Psychosomatic Medicine.
76(3):A2-A3
2014
Racial and ethnic differences in older adults with knee osteoarthritis.
Arthritis & rheumatology (Hoboken, N.J.).
66(7):1800-10
[DOI] 10.1002/art.38620.
[PMID] 24729357.
2014
Site-specific differences in the association between plantar tactile perception and mobility function in older adults.
Frontiers in aging neuroscience.
6
[DOI] 10.3389/fnagi.2014.00068.
[PMID] 24782765.
2014
Temporal summation of pain as a prospective predictor of clinical pain severity in adults aged 45 years and older with knee osteoarthritis: ethnic differences.
Psychosomatic medicine.
76(4):302-10
[DOI] 10.1097/PSY.0000000000000058.
[PMID] 24804882.
2013
Age-Related Changes in Central and Peripheral Mechanisms of Pain
Gerontologist.
53(1)
2013
Experimental pain phenotype profiles in a racially and ethnically diverse sample of healthy adults.
Pain medicine (Malden, Mass.).
14(11):1708-18
[DOI] 10.1111/pme.12203.
[PMID] 23889771.
2013
Experimental Pain Sensitivity Differs as a Function of Clinical Pain Severity in Symptomatic Knee Osteoarthritis (Vol 21, Pg 1243, 2013)
Osteoarthritis and Cartilage.
21(11)
[DOI] 10.1016/j.joca.2013.09.001.
2013
Experimental pain sensitivity differs as a function of clinical pain severity in symptomatic knee osteoarthritis.
Osteoarthritis and cartilage.
21(9):1243-52
[DOI] 10.1016/j.joca.2013.05.015.
[PMID] 23973137.
2013
Metabolite concentrations in the anterior cingulate cortex predict high neuropathic pain impact after spinal cord injury.
Pain.
154(2):204-212
[DOI] 10.1016/j.pain.2012.07.022.
[PMID] 23141478.
2013
Offset analgesia is reduced in older adults.
Pain.
154(11):2381-2387
[DOI] 10.1016/j.pain.2013.07.015.
[PMID] 23872117.
2013
Perceived racial discrimination, but not mistrust of medical researchers, predicts the heat pain tolerance of African Americans with symptomatic knee osteoarthritis.
Health psychology : official journal of the Division of Health Psychology, American Psychological Association.
32(11):1117-26
[DOI] 10.1037/a0031592.
[PMID] 24219416.
2013
Psychological profiles and pain characteristics of older adults with knee osteoarthritis.
Arthritis care & research.
65(11):1786-94
[PMID] 23861288.
2013
Psychometric evaluation of the Spanish version of the MPI-SCI.
Spinal cord.
51(7):538-52
[DOI] 10.1038/sc.2013.21.
[PMID] 23608807.
2013
Psychosocial Profiles and Pain Characteristics of Older Adults With Knee Osteoarthritis
Journal of Pain.
14
2013
Reproductive Endocrinology and Infertility Match: a Survey of the 2011-2012 Applicant Pool
Fertility and Sterility.
99
2013
The association of greater dispositional optimism with less endogenous pain facilitation is indirectly transmitted through lower levels of pain catastrophizing.
The journal of pain.
14(2):126-35
[DOI] 10.1016/j.jpain.2012.10.007.
[PMID] 23218934.
2013
The Role of Race and Sex On Experimental Pain Sensitivity in Individuals With Symptomatic Knee Osteoarthritis
Journal of Pain.
14
2012
Decreased spinothalamic and dorsal column medial lemniscus-mediated function is associated with neuropathic pain after spinal cord injury.
Journal of neurotrauma.
29(17):2706-15
[DOI] 10.1089/neu.2012.2343.
[PMID] 22845918.
2012
Immune biomarker response depends on choice of experimental pain stimulus in healthy adults: a preliminary study.
Pain research and treatment.
2012
[DOI] 10.1155/2012/538739.
[PMID] 23213513.
2011
Prognostic value of beta-human chorionic gonadotropin is dependent on day of embryo transfer during in vitro fertilization.
Fertility and sterility.
96(6):1362-6
[DOI] 10.1016/j.fertnstert.2011.09.042.
[PMID] 22047663.
2009
Relationship between pain characteristics and pain adaptation type in persons with SCI.
Journal of rehabilitation research and development.
46(1):43-56
[PMID] 19533519.
2007
Chronic pain after spinal cord injury: what characteristics make some pains more disturbing than others?
Journal of rehabilitation research and development.
44(5):703-15
[PMID] 17943682.
2007
Psychosocial subgroups in persons with spinal cord injuries and chronic pain.
Archives of physical medicine and rehabilitation.
88(12):1628-35
[PMID] 18047878.
2006
Internal consistency, stability, and validity of the spinal cord injury version of the multidimensional pain inventory.
Archives of physical medicine and rehabilitation.
87(4):516-23
[PMID] 16571391.
2005
Chronicity of pain associated with spinal cord injury: A longitudinal analysis.
Journal of rehabilitation research and development.
42(5):585-94
[PMID] 16586184.
2005
Postoperative fibrosis after surgical treatment of the porcine spinal cord: a comparison of dural substitutes. Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2004.
Journal of neurosurgery. Spine.
2(1):50-4
[PMID] 15658126.
2004
Is there a relationship between chronic pain and autonomic dysreflexia in persons with cervical spinal cord injury?
Journal of neurotrauma.
21(2):195-204
[PMID] 15000760.
Grants
Aug 2024
ACTIVE
University of Florida Partnerships Across Interdisciplinary Networks: Training through Engineering, epidemiology & Addiction Medicine (UF PAIN TEAM)
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAMS
Aug 2024
ACTIVE
University of Florida Partnerships Across Interdisciplinary Networks: Training through Engineering, epidemiology & Addiction Medicine (UF PAIN TEAM)
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAMS
Jun 2024
ACTIVE
Machine learning-based brain aging morphological signatures of chronic musculoskeletal pain
Role: Other
Funding: NATL INST OF HLTH NIA
Sep 2023
– Aug 2024
Collaborative for REsearch to Advance TMD Evidence (CREATE)
Role: Co-Investigator
Funding: UNIV OF PITTSBURGH
via NATL INST OF HLTH NIDCR
May 2023
ACTIVE
The potential of oxytocin to reduce opioid abuse liability and pain among older adults
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDA
May 2023
– Apr 2024
Pain and Nutrition in Dementia and Alzheimers PANDA
Role: Other
Funding: NATL INST OF HLTH NIA
Apr 2023
ACTIVE
The impact of structural racism and discrimination on chronic pain in Black or African American older adults: Biopsychosocial mechanisms
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Sep 2022
ACTIVE
Innervation of the knee and TMJ
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAMS
Aug 2022
– Dec 2023
Integrating Biomechanics and Experimental Pain to Understand Compensatory Mechanisms in Symptomatic Carpometacarpal Osteoarthritis
Role: Other
Funding: NATL INST OF HLTH NIA
Jun 2022
ACTIVE
University of Florida Claude D. Pepper Older Americans Independence Center
Role: Other
Funding: NATL INST OF HLTH NIA
Jun 2022
ACTIVE
Biopsychosocial pain predictors of mobility decline in aging
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Apr 2022
ACTIVE
Carpometacarpal Osteoarthritis: Understanding the Intersection of Muscle Mechanics, Joint Instability, and Pain
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAMS
Jan 2022
ACTIVE
Opioid-Sparing and Pain-Reducing Properties of Syntocinon: A Dose-Effect Determination
Role: Other
Funding: NATL INST OF HLTH NIDA
Aug 2021
ACTIVE
SF2UF: The Bridges to the Baccalaureate partnership between Santa Fe College and the University of Florida
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Sep 2020
ACTIVE
the Integrative and Multidisciplinary Pain and Aging Research Training (IMPART) Program
Role: Other
Funding: NATL INST OF HLTH NIA
Jul 2020
– Jul 2021
Contributions of biopsychosocial factors in sickle cell disease pain
Role: Other
Funding: NATL INST OF HLTH NHLBI
May 2020
ACTIVE
Biobehavioral basis of knee osteoarthritis pain
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Sep 2018
ACTIVE
Multimodal imaging of brain activity to investigate walking and mobility decline in older adults
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Aug 2018
ACTIVE
Mechanisms of Oxytocins Analgesia in Older Adults
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Apr 2018
– Mar 2024
Neural mechanisms underlying psychosocial contributions to ethnic group differences in pain
Role: Other
Funding: NATL INST OF HLTH NINDS
Apr 2017
– Mar 2022
University of Florida Claude D. Pepper Older Americans Independence Center (OAIC)
Role: Project Manager
Funding: NATL INST OF HLTH NIA
Apr 2016
– Mar 2017
Claude D Pepper Older Americans Independence Center
Role: Project Manager
Funding: NATL INST OF HLTH NIA
May 2015
– Aug 2020
Neuroimaging age-related changes in pain modulation
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Apr 2015
– Mar 2016
Claude D. Pepper Older Americans Independence Center
Role: Project Manager
Funding: NATL INST OF HLTH NIA
Jul 2007
– Aug 2016
Clinical and Translational Science Institute
Role: Project Manager
Funding: UF RESEARCH FOU
Education
Postdoctoral Fellowship in Translational Pain Research
2012
·
University of Florida
Ph.D. Neuroscience
2011
·
University of Miami
M.S. Epidemiology & Public Health
2004
·
University of Miami
B.S. Microbiology & Cell Science
2001
·
University of Florida
Contact Details
Phones:
- Business:
- (352) 294-5845
Emails:
- Business:
- cryeni@ufl.edu
Addresses:
- Business Mailing:
-
P.O. BOX 103628
GAINESVILLE FL 326100001 - Business Street:
-
2004 MOWRY RD
GAINESVILLE FL 32611