July 2023 to June 2024

May/June 2024

PROJECT: “Longitudinal examination of changes in Medicaid adult dental coverage and spillover effects on children”
University of Iowa, NIH/NIDRCR R03DE031782
$43,155 for Two Years

PRINICPAL INVESTIGATOR
Dr. Astha Singhal, College of Dentistry, Department of Community Dentistry and Behavioral Science

Astha Singhal

PROJECT: “Investigation of the virulence diversity of P. gingivalis strains”
UFCD Faculty Seed Grant
$20,000 for One Year

PRINICPAL INVESTIGATOR
Dr. Ann Progulske-Fox, College of Dentistry, Department of Oral Biology

Ann Progulske-Fox

PROJECT:Role of understudied aGPCRs in orofacial neuropathic pain
NIH/NIDCR R21DE033639
$419,375 for Two Years

PRINCIPAL INVESTIGATORS
Dr. Robert M. Caudle, Multi PI, College of Dentistry, Department of Oral and Maxillofacial Surgery
Dr. Basak Ayaz, MultiPI, College of Dentistry, Department of Oral and Maxillofacial Surgery

Dr. Robert Caudle
Basak Ayaz

PROJECT: “AADOCR Delta Dental Institute Oral Health Equity Research Award”
American Association for Dental, Oral, and Craniofacial Research
$25,000 for One Year

PRINICPAL INVESTIGATOR
Dr. Astha Singhal, College of Dentistry, Department of Community Dentistry and Behavioral Science

Astha Singhal

PROJECT: Machine learning-based brain aging morphological signatures of chronic musculoskeletal pain
NIH/NIA K01AG083228
$631,665 for Five Years

PRINCIPAL INVESTIGATOR
Dr. Pedro Valdes Hernandez, College of Dentistry, Department of Community Dentistry and Behavioral Science

MENTORS
Dr. Yenisel Cruz-Almeida, Mentor, College of Dentistry, Department of Community Dentistry and Behavioral Science
Dr. Roger B. Fillingim, Co-Mentor, College of Dentistry, Department of Community Dentistry and Behavioral Science
Dr. Qing Terry Lu, Co-Mentor, College of Public Health and Health Professions, Department of Biostatistics
Dr. Mattia Prosperi, Co-Mentor, College of Public Health and Health Professions, Office of the Dean

Pedro Valdes Hernandez
Yenisel Cruz-Almeida

March/April 2024


PROJECT:The effects of sublingual formulations of buprenorphine on dental decay
UFCD Student Seed Grant
$3,000 for one year

PRINCIPAL INVESTIGATOR
Kyle Kasparian, 4th Year DMD/PhD Student

MENTORS
Dr. Christopher R. McCurdy, Mentor, College of Pharmacy, Department of Medicinal Chemistry
Dr. Jacqueline Abranches, Co-Mentor, College of Dentistry, Department of Restorative Dental Sciences

Kyle Kasparian
Jacqueline Abranches

PROJECT: AI for prediction of location and severity of impacted maxillary teeth
American Association of Orthodontic Foundation
$20,000 for one year AGR00030856

PRINCIPAL INVESTIGATOR
Dr. Sarah Abu Arqub, College of Dentistry, Department of Orthodontics

Sarah H Abu Arqub

PROJECT:A randomized clinical trial to assess the efficacy of reducing the aligners’ wear protocol
American Association of Orthodontic Foundation
$5,800 for One Year

PRINCIPAL INVESTIGATOR
Dr. Alexandra Brown, Resident, College of Dentistry, Department of Orthodontics

MENTOR
Dr. Sarah Abu Arqub, College of Dentistry, Department of Orthodontics

Alexandra Brown
Sarah H Abu Arqub

January/February 2024


PROJECT:Chemical and Biological Evaluation of Long-Wavelength Light-Cured Biomaterials
UFCD Student Seed Grant
$3,000 for one year

PRINCIPAL INVESTIGATOR
Eden Sabag, 3rd Year DMD Student

MENTOR
Dr. Dayane Oliveira, Mentor, College of Dentistry, Department of Orthodontics

Eden Sabag
Dayane Oliveira

November/December 2023


PROJECT: “Prediction of location and severity of impacted maxillary teeth – Artificial intelligence algorithm using panoramic radiographs”
UFCD Student Seed Grant
$2,500 for one year

PRINCIPAL INVESTIGATOR
Dr. Adrienne Kramer, Resident, College of Dentistry, Department of Orthodontics

MENTOR
Dr. Sarah Abu Arqub, College of Dentistry, Department of Orthodontics

Adrienne Saltos Kramer

PROJECT: “A randomized clinical trial to assess the efficacy of reducing the aligners’ wear protocol”
UFCD Student Seed Grant
$2,500 for one year

PRINCIPAL INVESTIGATOR
Dr. Alexandra Brown, Resident, College of Dentistry, Department of Orthodontics

MENTOR
Dr. Sarah Abu Arqub, College of Dentistry, Department of Orthodontics

Alexandra Brown
Sarah H Abu Arqub

PROJECT: “Evaluation of color science education on shade selection performance among dental providers”
UFCD Student Seed Grant
$2,861.77 for one year

PRINCIPAL INVESTIGATOR
Dr. Vanessa Schussler, Resident, College of Dentistry, Department of Restorative Dental Sciences

MENTORS
Dr. Dayane Oliveira, College of Dentistry, Department of Restorative Dental Sciences
Dr. Patricia Pereira, College of Dentistry, Department of Restorative Dental Sciences

Vanessa Schussler

PROJECT: “Development of Opportunities for Research (DOOR) in Dental Schools: Future Academic Interdisciplinary Workforce and Collaborators for the National Dental Practice-Based Research Network (PBRN)”
NIH/NIDCR U01DE0332621
$3,692,175 for five years

PRINCIPAL INVESTIGATOR
Dr. Daniel McNeil, College of Dentistry, Department of Community Dentistry and Behavioral Sciences

CO INVESTIGATORS
Dr. Valeria V. Gordan, College of Dentistry, Department of Restorative Dentistry Sciences
Dr. Karin C. Schey, College of Dentistry, Department of Periodontics
Dr. Patricia N. Pereira, College of Dentistry, Department of Restorative Dental Sciences
Dr. Joseph L. Riley, College of Dentistry, Department of Community Dentistry and Behavioral Science
Dr. Zoidis Panagiotis, College of Dentistry, Restorative Dental Science, Clinic Administration
Dr. Cynthia S. Garvan, College of Medicine, Department of Anesthesiology
Dr. Roberta Pileggi, College of Dentistry, Department of Endodontics
Dr. Roger B. Fillingim, College of Dentistry, Department of Community Dentistry and Behavioral Science
Dr. William D. Duncan, College of Dentistry, Department of Community Dentistry and Behavioral Science
Dr. Li Chen, College of Public Health and Health Professions & College of Medicine, Department of Biostatistics
Dr. Emily Jo Bartley, College of Dentistry, Department of Community Dentistry and Behavioral Science

Daniel McNeil

PROJECT: “Regulation of KSHV infection through protein degradation”
UFCD Faculty Seed Grant
$20,000 for one year

PRINCIPAL INVESTIGATOR
Dr. Zsolt Toth, College of Dentistry, Department of Oral Biology

Dr. Zsolt Toth

PROJECT: “AHEC (R1) Tobacco Training and Cessation Program”
UF AHEC Program Office, FLDOH/COTHI
$13,975 for one year

PRINCIPAL INVESTIGATOR
Dr. Olga Ensz, College of Dentistry, Department of Community Dentistry and Behavioral Sciences

CO INVESTIGATOR
Dr. Karin Schey, Faculty, College of Dentistry, Department of Periodontology

Dr. Olga Ensz

September/October 2023


PROJECT: “Mechanisms of metal ion homeostasis of oral Streptococci”
NIH/NIDCR R01DE032555
$2,257,662 for five years

PRINCIPAL INVESTIGATOR
Dr. Jose A. Lemos, College of Dentistry, Department of Oral Biology

CO INVESTIGATORS
Dr. Jacqueline Abranches, College of Dentistry, Department of Oral Biology
Dr. Chenglon Li, College of Pharmacy, Department of Medicinal Chemistry
Dr. Robert W. Huigens, College of Pharmacy, Department of Medicinal Chemistry

Jose A Lemos

PROJECT: “A multisystem resilience approach in the assessment of postsurgical pain trajectories”
NIH/NIAMS R01AR081835
$2,996,203 for five years

PRINCIPAL INVESTIGATOR
Dr. Emily Bartley, College of Dentistry, Department of Community Dentistry and Behavioral Sciences

CO INVESTIGATORS
Dr. Hernan Augusto Prieto Saavedra, College of Medicine, Department of Orthopaedics and Rehabilitation
Dr. Francois Paul Philippe Modave, College of Medicine, Department of Anesthesiology
Dr. Patrick J. Tighe, College of Medicine, Department of Anesthesiology
Dr. Terrie Vasilopoulos, College of Medicine, Department of Anesthesiology

Emily J Bartley

PROJECT: “Development of a provider centered intervention for non-traumatic dental condition management in the emergency department”
NIH/NIDCR K99DE031723
$200,943 for two years

PRINCIPAL INVESTIGATOR
Tumader Khouja, College of Dentistry, Department of Community Dentistry and Behavioral Sciences

MENTORS
Dr. Roger B. Fillingim, Mentor, College of Dentistry, Department of Community Dentistry and Behavioral Sciences
Dr. A. Isabel Garcia, Co-Mentor, College of Dentistry, Dean
Dr. Jiang Bian, Co-Mentor, College of Medicine, Biomedical Informatics

Tumader Khouja
Roger Fillingim

PROJECT: “Collaborative for research to advance TMD evidence (CREATE)”
University of Pittsburgh, NIH/NIDCR R34DE033591
$93,832 for one year

PRINCIPAL INVESTIGATOR
Dr. Roger B. Fillingim, College of Dentistry, Department of Community Dentistry and Behavioral Sciences

CO INVESTIGATORS
Dr. Yenisel Cruz-Almeida, College of Dentistry, Department of Community Dentistry and Behavioral Sciences
Dr. John K Neuber, College of Dentistry, Department of Orthodontics
Dr. Kyle Allen, College of Engineering, Department of Biomedical Engineering

Roger Fillingim

PROJECT: “Ryan White HIV/AIDS dental reimbursements”
HRSA T22HA49972
$5,971 for one year

PRINCIPAL INVESTIGATOR
Dr. Frank A Catalanotto, College of Dentistry, Department of Community Dentistry and Behavioral Sciences

Dr. Frank Catalanotto

PROJECT: “Biopsychosocial influence on shoulder pain”
Arizona State University, NIH/NIAMS R01AR081796
$92,880 for five years

PRINCIPAL INVESTIGATOR
Dr. Roger B Fillingim, College of Dentistry, Department of Community Dentistry and Behavioral Sciences

Roger Fillingim

PROJECT: “BA220315: Extracellular vesicles as biomarkers, mediators of immune dysfunction and universal countermeasures against radiation syndrome and associated polytrauma”
DOD US Army Medical Research and Development, HT9425-23-1-0913
$78,443 for three years

CO INVESTIGATOR
Dr. Shannon Wallet, Co-I, College of Dentistry, Department of Oral Biology

INVESTIGATORS
Dr. Robert Maile, PI, College of Medicine, Department of Surgery
Dr. Ian Driscoll, Co-I, College of Medicine, Department of Surgery

Shannon M Wallet

PROJECT: “PRK sensing of mitochondrial dsRNA in childhood Sjogrens disease”
NIH/NIDCR R01DE032707
$2,980,684 for five years

PRINCIPAL INVESTIGATOR
Dr. Seunghee Cha, College of Dentistry, Department of Oral and Maxillofacial Diagnostic Sciences

CO INVESTIGATORS
Dr. Indraneel Bhattacharyya, College of Dentistry, Department of Oral and Maxillofacial Diagnostic Sciences
Dr. Weizhou Zhang, College of Medicine, Department of Pathology
Dr. Westley Hubbard Reeves, College of Medicine, Department of Rheumatology

Seunghee Cha

July/August 2023


PROJECT: “Machine learning model to assess the external apical root resorption from the CBCT image”
American Association of Orthodontists Foundation AGR00028177
$30,000 for one year

PRINICPAL INVESTIGATOR
Dr. Divakar Karanth, College of Dentistry, Department of Orthodontics

Divakar Karanth

PROJECT: “Comparative evaluation of cannabinoids and opioids for treating chronic pain in aged subjects”
Consortium for Medical Marijuana Clinical Outcomes Research FY24 MMJCOR
$64,822 for one year

PRINICPAL INVESTIGATOR
Dr. Niall Murphy, College of Dentistry, Department of Orthodontics Research

CO INVESTIGATOR
Dr. Abhesheak Sharma, College of Pharmacy, Department of Pharmaceutics

Niall Murphy

PROJECT: “Defining the role of sphingolipids of Porphyromonas gingivalis outer membrane vesicle uptake and elicited inflammation”
NIH/NIDCR F31DE033255
$88,525 for two years

PRINCIPAL INVESTIGATOR
Zavier Eure, PhD Candidate, College of Dentistry, Department of Oral Biology

MENTOR
Dr. Frank Gibson, College of Dentistry, Department of Oral Biology

Zavier Eure
Frank Gibson

PROJECT: “Determination of structure-function relationships and role in virulence of a MerR-type regulator that mediates zinc tolerance in Streptococcus mutans”
NIH/NIDCR F31DE032899
$86,324 for two years

PRINCIPAL INVESTIGATOR
Alexandra Peterson, PhD Candidate, College of Dentistry, Department of Oral Biology

MENTOR
Dr. Jose A. Lemos, College of Dentistry, Department of Oral Biology

Alexandra Peterson
Jose A Lemos

PROJECT: ““Interspecies interactions between Enterococcus faecalis and lactobacilli in the female genitourinary tract”
UFCD Post-Doc Seed Grant
$5,000 for one ye

PRINCIPAL INVESTIGATOR
Dr. Kaylie Lam, College of Dentistry, Department of Oral Biology

MENTOR
Dr. Jose A. Lemos, College of Dentistry, Department of Oral Biology

Kaylie L N Lam
Jose A Lemos

PROJECT: “Susceptibility patterns for grade C. periodontitis in young individuals”
University of Kentucky, NIH/NIDCR U01DE 031223
$385,747 for five years

CO INVESTIGATORS
Dr. Olga S. Ensz, College of Dentistry, Department of Community Dentistry and Behavioral Sciences
Tina Treloar, College of Dentistry, Department of Community Dentistry and Behavioral Sciences

PRINCIPAL INVESTIGATOR
Dr. Margaret R. Wallace, College of Medicine, Department of Molecular Genetics & Microbiology

Dr. Olga Ensz
Tina Treloar

PROJECT: “Role of state Medicaid policies in improving access to dental care among low-income adults”
NIH/NIDCR K08DE027720
$60,501 for one year

PRINICPAL INVESTIGATOR
Dr. Astha Singhal, College of Dentistry, Department of Community Dentistry and Behavioral Sciences

Astha Singhal

PROJECT: “Sleep and circadian rhythm disturbances as risk and progression factors for multiple chronic pain condition”
Arizona State University, NIH/NINDS R01NS129887
$194,513 for five year

PRINICPAL INVESTATOR
Dr. Roger B Fillingim, College of Dentistry, Department of Community Dentistry and Behavioral Sciences

Roger Fillingim

PROJECT: “Cannabidiol and oxycodone interactions on pain and mobility in aged rats”
PESC Pilot Study NIH/NIA P30AG028740
$51,850 for two years

PRINCIPAL INVESTIGATOR
Dr. Ariana Brice-Tutt, College of Dentistry, Department of Orthodontics

MENTOR
Dr. John Neubert, College of Dentistry, Department of Orthodontics

Ariana C Brice-Tutt
Dr. John Neubert

PROJECT: “Pain, multimorbidity, opioid-drug interactions and risk for opioid use disorder or overdose in older adults”
Ohio State University, DHHS/AHRQ R01HS029001
$502,887 for four years

PRINCIPAL INVESTIGATOR
Dr. Roger B Fillingim, College of Dentistry, Department of Community Dentistry and Behavioral Sciences

CO INVESTIGATORS
Dr. Siegfried O. Schmidt, College of Medicine, Department of Community Health & Family Medicine, Springhill
Dr. Stephan Schmidt, College of Pharmacy, Department of Pharmaceutics
Dr. Almut Gertrud Winterstein, College of Pharmacy, Department of Pharmaceutical Outcomes & Policy

Roger Fillingim

PROJECT: “Nitric oxide-releasing hyaluronic acid therapeutics for treating periodontal disease”
University of North Carolina at Chapel Hill, NIH/NIDCR R01DE032060
$984,314 for five years

PRINCIPAL INVESTIGATOR
Dr. Shannon Wallet, College of Dentistry, Department of Oral Biology

CO INVESTIGATOR
Dr. Robert Maile, College of Medicine, Department of Surgery

Shannon M Wallet

PROJECT: “Effects of pregnancy and postpartum Medicaid dental benefit generosity on use of dental services”
NIH/NIDCR R03DE033075
$307,326 for two years

PRINCIPAL INVESTIGATOR
Dr. Astha Singhal, College of Dentistry, Department of Community Dentistry and Behavioral Sciences

Astha Singhal

PROJECT: “Photobiomodulation for the management of Temporomandibular disorder pain”
NIH/NIDCR UH3DE030433
$3,322,546 for five years

PRINCIPAL INVESTIGATORS
Dr. Margarete Ribeiro Dasilva, Multi PI, College of Dentistry, Department of Restorative Dental Sciences, Prosthodontics Division
Dr. Roger B. Fillingim, Multi PI, College of Dentistry, Department of Community Dentistry and Behavioral Sciences

CO INVESTIGATORS
Dr. Cesar A. Migliorati, College of Dentistry, Department of Oral and Maxillofacial Diagnostic Sciences
Dr. Frank Gibson, College of Dentistry, Department of Oral Biology
Dr. Zhigang Li, College of Public Health and Professions, Department of Biostatistics

Margarete Ribeiro Dasilva
Roger Fillingim