Orthodontics

Phone: 352-273-5700 Room: D7-19 P.O. Box 100444

Dr. C. Dolce

  • Bone remodeling during orthodontic tooth movement
  • Gene activation in osteoblasts in response to mechanical stimulation

Dr. L.S. Holliday

  • Activation of osteoclastic bone resorption
  • Integrin-associated signaling in osteoclasts
  • Phosphatidylinositol 3-kinase
  • Cytoskeletal dynamics in osteoclasts
  • Structure transport and function of vacuolar H+ ATPase
  • Adeno-associated virus in the treatment of osteoclast-involved disease

Dr. J. Morris-Wiman

  • Morphogenesis and differentiation of taste-related oral structures
  • Nerve muscle interaction in jaw muscle development
  • Role of extracellular matrix and matrix metalloproteinases in craniofacial development

Dr. J. Neubert

  • Clinical and Basic Science
  • Investigation of inflammatory and neuropathic mechanisms relating to peripheral pain
  • Translating these laboratory findings into therapeutics for chronic pain sufferers
  • Developing a collaborative network of research relating to temporomandibular joint disorders and other orofacial pain disorders

Dr. T.T. Wheeler

  • Orthodontic treatment outcomes
  • Orthodontic tooth movement

Dr. C.G. Widmer

  • Motor control mechanisms for jaw muscles
  • Jaw and trigeminofacial reflexes
  • Research diagnostic criteria for temporomandibular disorders and other orofacial pain conditions
  • Nerve-muscle interactions during jaw muscle development
  • Biological basis for masticatory muscle pain

Dr. R.P. Yezierski

  • Pain mechanisms related to the effects of age on pain sensitivity
  • the role of changes in immune function, HPA axis, and different transmitter systems on varying sensitivity to pain in animals of different ages
  • How these changes are affected during normal aging, under pathological conditions and during conditions of stress are also being investigated
  • Interest is in evaluating these changes using complex behavioral assessment strategies that involve cortical processing and decision making
  • Plasticity and glia responses to acute and chronic pain conditions at different ages and the impact of cytokines and other inflammatory molecules in the development of chronic pain conditions